Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723243 | 0.96 | CTSL (0.43) | CTSLCTSBCTSSCTSKMMP2 | |
| Trifluoroacetic Acid SCHEMBL7733845 | 0.89 | LMNA (0.39) | MMP2CTSCLNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7734181 | 0.89 | OPRK1 (0.37) | CTSLCTSBMMP2CTSCLNPEP | |
| Trifluoroacetic Acid SCHEMBL7731111 | 0.89 | MMP2 (0.38) | CTSLMMP2CTSCPTPN2PTPN1 | |
| SCHEMBL7732041 | 0.87 | CTSL (0.39) | CTSLCTSBCTSSCTSKMMP2 | |
| SCHEMBL7732452 | 0.84 | LMNA (0.42) | MMP2CTSCLNPEPERAP2ERAP1 | |
| SCHEMBL7730106 | 0.84 | CTSC (0.38) | CTSBCTSSCTSKMMP2CTSC | |
| Trifluoroacetic Acid SCHEMBL7731949 | 0.81 | FAAH (0.40) | CTSLMMP2CTSCLNPEPERAP2 | |
| SCHEMBL7732434 | 0.78 | CTSL (0.43) | CTSLCTSBCTSSCTSKNPC1 | |
| SCHEMBL7732045 | 0.78 | CTSL (0.36) | CTSLCTSBCTSSCTSKPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |