Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267270 | 0.83 | SMN1; SMN2 (0.54) | POLBSMN1; SMN2ALDH1A1CHRM2KDM4E | |
| SCHEMBL7725659 | 0.79 | SMN1; SMN2 (0.37) | POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7728377 | 0.79 | POLB (0.44) | POLBSMN1; SMN2LMNAGPR139ALDH1A1 | |
| SCHEMBL7729289 | 0.79 | SMN1; SMN2 (0.37) | POLBSMN1; SMN2TRPA1LMNACHRM1 | |
| SCHEMBL5266343 | 0.78 | SMN1; SMN2 (0.49) | POLBSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL7728348 | 0.77 | SMN1; SMN2 (0.38) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7194394 | 0.75 | SMN1; SMN2 (0.45) | POLBSMN1; SMN2MEN1KMT2AADRB2 | |
| SCHEMBL11884336 | 0.73 | SMN1; SMN2 (0.58) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7193740 | 0.73 | P2RX7 (0.44) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5268596 | 0.73 | CASR (0.55) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403832-B1 | MIXING ACID WITH AMINE, PRECIPITATING SALT, AND FILTERING; GOOD OPTICAL PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |