Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193740 | 0.87 | P2RX7 (0.44) | SMN1; SMN2P2RX7KMT2AMEN1NPC1 | |
| SCHEMBL5269356 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2P2RX7KMT2AMEN1RXFP1 | |
| SCHEMBL7194394 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2P2RX7KMT2AMEN1NPC1 | |
| SCHEMBL7728512 | 0.77 | POLB (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1CHRM2 | |
| SCHEMBL5274512 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7732172 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2P2RX7KMT2AMEN1NPC1 | |
| SCHEMBL7728377 | 0.75 | POLB (0.44) | SMN1; SMN2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7729289 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5269340 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2P2RX7KMT2AMEN1ALDH1A1 | |
| SCHEMBL7194520 | 0.70 | RAB9A (0.48) | SMN1; SMN2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403832-B1 | MIXING ACID WITH AMINE, PRECIPITATING SALT, AND FILTERING; GOOD OPTICAL PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |