Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PLEC | Q15149 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269294 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBCHRM2CYP1A2CYP2D6 | |
| SCHEMBL7728512 | 0.79 | POLB (0.42) | SMN1; SMN2POLBCHRM2MEN1ALDH1A1 | |
| SCHEMBL5274540 | 0.75 | RAB9A (0.39) | SMN1; SMN2POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL7725659 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBMEN1KMT2AHPGD | |
| SCHEMBL7728377 | 0.74 | POLB (0.44) | SMN1; SMN2POLBCYP2D6MEN1ALDH1A1 | |
| SCHEMBL7728348 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2POLBCHRM2MEN1ALDH1A1 | |
| SCHEMBL7194394 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL5272049 | 0.70 | POLB (0.46) | SMN1; SMN2POLBCYP1A2CYP2D6MEN1 | |
| SCHEMBL5270099 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2POLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5267654 | 0.70 | CASR (0.53) | SMN1; SMN2MEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403832-B1 | MIXING ACID WITH AMINE, PRECIPITATING SALT, AND FILTERING; GOOD OPTICAL PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |