Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7728667

NCC(=O)Nc1ccc(Cc2ccccc2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.57
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56
POLB P06746 1/20 0.50
CHIT1 Q13231 1/20 0.48
LMNA P02545 1/20 0.47
EPHX2 P34913 1/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
MLYCD O95822 2/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
MAPT P10636 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6932239 0.81 CA1 (0.50) LTA4HPOLBCHIT1LMNACA1
Trifluoroacetic Acid SCHEMBL29406683 0.80 ALDH1A1 (0.51) LTA4HPOLBLMNACA1CA2
Trifluoroacetic Acid SCHEMBL6932230 0.79 MLYCD (0.48) LTA4HPOLBCHIT1CA1CA2
SCHEMBL188327 0.77 LTA4H (0.64) LTA4HEPHX2CA1CA2MAPT
Trifluoroacetic Acid SCHEMBL27715018 0.76 EPHX2 (0.79) LMNAEPHX2CA1CA2CA12
SCHEMBL7373037 0.76 HDAC4 (0.79) LTA4HPOLBHDAC3HDAC4HDAC1
SCHEMBL6932233 0.76 CA1 (0.57) LTA4HEPHX2CA1CA2MLYCD
SCHEMBL5175200 0.76 EPHX2 (0.79) SLC1A3SLC1A2SLC1A1POLBEPHX2
SCHEMBL19962686 0.75 POLB (0.65) LTA4HSLC1A3SLC1A2SLC1A1POLB
Trifluoroacetic Acid SCHEMBL7760563 0.75 AOC3 (0.60) LMNACA1CA2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399629-B1 PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY MICROCIDE PHARMACEUTICALS, INC. 2002-06-04 US disclosed
WO-2000001714-A1 EFFLUX PUMP INHIBITORS MICROCIDE PHARMACEUTICALS, INC. (US) 2000-01-13 WO disclosed