Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729019 | 0.93 | SMYD3 (0.41) | SMYD3CHEK2GID4EGLN1DPP8 | |
| SCHEMBL7729522 | 0.86 | LPAR2 (0.42) | TSHRRAF1BRAFTDP1ABL1 | |
| SCHEMBL8144435 | 0.84 | CACNA1G (0.40) | RAD52UBE2NGAAPKMTSHR | |
| SCHEMBL7732752 | 0.83 | GID4 (0.41) | SMYD3CHEK2RAD52UBE2NGID4 | |
| SCHEMBL7731211 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL21436230 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL7729500 | 0.79 | ALDH1A1 (0.40) | KDM4ETDP1ABL1GSK3B | |
| SCHEMBL7723308 | 0.77 | CACNA1G (0.40) | GID4GAATSHRDPP8DPP9 | |
| SCHEMBL7723513 | 0.77 | CACNA1G (0.40) | GID4GAATSHRDPP8DPP9 | |
| SCHEMBL2067985 | 0.76 | GID4 (0.41) | SMYD3GID4EGLN1TDP1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |