SCHEMBL772927

SCHEMBL772927

Oc1cccc2cc(Cl)ccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 8/20 0.59
HSD17B2 P37059 8/20 0.59
PLAU P00749 1/20 0.59
ESR1 P03372 2/20 0.55
ESR2 Q92731 2/20 0.55
CYP1A2 P05177 1/20 0.54
PYGL P06737 1/20 0.52
CYP2A6 P11509 1/20 0.48
POLA1 P09884 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPKAPK2 P49137 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
NQO2 P16083 1/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Cresol SCHEMBL5528682 0.86 HSD17B1 (0.56) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL19460401 0.84 CYP2A6 (0.47) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL29291191 0.83 CYP2A6 (0.45) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL4960994 0.83 CTDSP1 (0.59) HSD17B1HSD17B2PLAUESR1ESR2
Parachlorophenol SCHEMBL5534621 0.79 HSD17B1 (0.56) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL16632629 0.79 TTR (0.45) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL15451 0.77 HSD17B1 (0.70) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL29738652 0.77 HSD17B1 (0.70) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL29364213 0.77 HSD17B1 (0.70) HSD17B1HSD17B2PLAUESR1ESR2
SCHEMBL444105 0.77 HSD17B1 (0.84) HSD17B1HSD17B2PLAUESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211414-B2 Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity VISIGEN BIOTECHNOLOGIES, INC. (US) 2007-05-01 US claimed
US-20260078111-A1 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2026-03-19 US disclosed
EP-4667474-A2 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2025-12-24 EP disclosed
EP-3909946-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-12-17 EP disclosed
EP-4630401-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF Rutgers, the State University of New Jersey (US) 2025-10-15 EP disclosed
WO-2024124023-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-06-13 WO disclosed
EP-4286491-A2 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2023-12-06 EP disclosed
EP-3415641-B1 METHOD FOR ANALYSIS OF MOLECULES PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2023-11-01 EP disclosed
CN-115703747-A Organic compound having spirofluorene structure for light emitting device, organic electroluminescent device 北京鼎材科技有限公司 2023-02-17 CN disclosed
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed
CN-1041526-C Naphthalene-ring resin, resin composition, and cured product thereof NIPPON KAYAKU KK (JP) 1999-01-06 CN disclosed
US-5780571-A RESIN OBTAINED BY CONDENSATION OF NAPHTHOL AND 4,4*-BIS/CHLOROMETHYL/BIPHENYL, OPTIONALLY REACTED WITH EPICHLOROHYDRIN NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-07-14 US disclosed
EP-0416038-B1 NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED TROPIX INC (US) 1997-03-26 EP disclosed
EP-0644216-B1 NAPHTHALENE-RING RESIN, RESIN COMPOSITION, AND CURED PRODUCT THEREOF NIPPON KAYAKU KK (JP) 1996-07-17 EP disclosed
EP-0644216-A1 NAPHTHALENE-RING RESIN, RESIN COMPOSITION, AND CURED PRODUCT THEREOF NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1995-03-22 EP disclosed
EP-0416038-A4 NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED 1992-02-26 EP disclosed
EP-0416038-A1 NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED. TROPIX INC (US) 1991-03-13 EP disclosed
US-4952707-A DECOMPOSITION TO LIGHT EMITTING FLUOROPHORE; ANALYSIS TROPIX, INC. (US) 1990-08-28 US disclosed
WO-1990000164-A1 NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED TROPIX, INC. (US) 1990-01-11 WO disclosed
US-3985731-A MICROBIOCIDES, MOTOR ACTIVITY INDUCERS, CNS STIMULANTS E. R. SQUIBB & SONS, INC. (US) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078111-A1 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF CA6, CA9, CA7 HSD17B1 68/4885HSD17B2 167/4885PLAU 2040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.