Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 3/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735915 | 0.97 | MALT1 (0.42) | MALT1CMA1XIAPMLXELANE | |
| SCHEMBL7736364 | 0.95 | MALT1 (0.40) | MALT1CMA1XIAPMLXELANE | |
| SCHEMBL7736683 | 0.95 | CASP3 (0.41) | MALT1CMA1ELANEKEAP1CALCRL | |
| SCHEMBL7736050 | 0.95 | CASP3 (0.41) | MALT1CMA1ELANEKEAP1CALCRL | |
| SCHEMBL7736353 | 0.95 | CASP3 (0.41) | MALT1CMA1ELANEKEAP1CALCRL | |
| SCHEMBL7736573 | 0.95 | CAPN1 (0.40) | MALT1CAPN1KEAP1CALCRLCASP3 | |
| SCHEMBL7728310 | 0.95 | CASP3 (0.43) | MALT1CMA1ELANEKEAP1CALCRL | |
| SCHEMBL7729363 | 0.93 | CALCRL (0.44) | MALT1CMA1ELANEKEAP1CALCRL | |
| SCHEMBL7736915 | 0.93 | KEAP1 (0.42) | MALT1CMA1ELANECAPN1KEAP1 | |
| SCHEMBL7736380 | 0.93 | ITGB3 (0.40) | MALT1CMA1ELANEKEAP1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |