Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729318 | 0.99 | FAAH (0.39) | FAAHTHRBS1PR1HTR2ARARB | |
| SCHEMBL7722643 | 0.96 | HDAC3 (0.33) | FAAHTHRBS1PR1PPARGPPARA | |
| SCHEMBL7722830 | 0.95 | THRB (0.40) | FAAHTHRBS1PR1HTR2ARARB | |
| SCHEMBL7731700 | 0.94 | THRB (0.39) | FAAHTHRBS1PR1HTR2ARARB | |
| SCHEMBL7729582 | 0.94 | HTR2A (0.41) | FAAHTHRBHTR2ARARBRARA | |
| SCHEMBL7729353 | 0.94 | THRB (0.39) | FAAHTHRBS1PR1HTR2ARARB | |
| SCHEMBL7735344 | 0.94 | HTR2A (0.41) | FAAHTHRBHTR2ARARBRARA | |
| SCHEMBL7732860 | 0.94 | HTR2A (0.41) | FAAHTHRBHTR2ARARBRARA | |
| SCHEMBL7722609 | 0.93 | THRB (0.39) | FAAHTHRBS1PR1HTR2ARARB | |
| SCHEMBL7735337 | 0.93 | HTR2A (0.40) | FAAHTHRBHTR2ARARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-6403534-B1 | HERBICIDES; 1-(2-CHLORO-4-FLUORO-5-(3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)-1,2,3,6 -TETRAHYDROPYRIMIDIN-1-YL) PHENOXY)CYCLOPROPANECARBOXYLATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |