Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729486 | 0.96 | FAAH (0.36) | HDAC3HDAC1HDAC2S1PR1FAAH | |
| SCHEMBL7729318 | 0.95 | FAAH (0.39) | S1PR1FAAHPPARGPPARATHRB | |
| SCHEMBL7730235 | 0.95 | S1PR1 (0.36) | S1PR1S1PR3PSEN1FAAHPPARG | |
| SCHEMBL7729353 | 0.93 | THRB (0.39) | S1PR1S1PR3PSEN1FAAHPPARG | |
| SCHEMBL7733324 | 0.93 | S1PR1 (0.35) | S1PR1S1PR3PSEN1FAAHPPARG | |
| SCHEMBL7731700 | 0.93 | THRB (0.39) | S1PR1S1PR3PSEN1FAAHPPARG | |
| SCHEMBL7733189 | 0.93 | S1PR1 (0.35) | S1PR1S1PR3PSEN1FAAHPPARG | |
| SCHEMBL7733328 | 0.92 | TSHR (0.33) | TSHRTHRBFFAR4EPHX2NR1H4 | |
| SCHEMBL7729381 | 0.91 | HTR2A (0.40) | FAAHPPARGPPARATHRB | |
| SCHEMBL7735337 | 0.91 | HTR2A (0.40) | FAAHPPARGPPARATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |