Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189644 | 0.92 | CDC25B (0.49) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL8192545 | 0.89 | RORB (0.47) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL415485 | 0.89 | KDM4E (0.55) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL8189911 | 0.86 | SMN1; SMN2 (0.55) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL11957361 | 0.85 | SMN1; SMN2 (0.49) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| Ethylene SCHEMBL27448159 | 0.85 | KDM4E (0.51) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL7666259 | 0.85 | KDM4E (0.47) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL418180 | 0.82 | SMN1; SMN2 (0.62) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8913939 | 0.82 | KDM4E (0.45) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL26056075 | 0.81 | SMN1; SMN2 (0.45) | KDM4ELMNAALOX15SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6478988-B1 | Photochromic substituted naphthopyran compounds | BMC VISION-EASE LENS, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1016702-A2 | Photochromic substituted naphthopyran compounds | BMC Vision-Ease Lens Inc. (US) | 2000-07-05 | — | — | EP | disclosed |