Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731008 | 0.97 | TSHR (0.35) | TSHREPHX2NR1H4HCRTR1HCRTR2 | |
| SCHEMBL7734959 | 0.91 | DAO (0.40) | TSHREPHX2NR1H4HCRTR1HCRTR2 | |
| SCHEMBL7722612 | 0.91 | PRMT6 (0.38) | TSHREPHX2NR1H4ALDH1A1KIF11 | |
| SCHEMBL7729295 | 0.90 | TSHR (0.35) | TSHREPHX2NR1H4HCRTR1HCRTR2 | |
| SCHEMBL7732166 | 0.90 | PPARD (0.35) | TSHREPHX2NR1H4HCRTR1HCRTR2 | |
| SCHEMBL7731615 | 0.89 | TSHR (0.35) | TSHREPHX2NR1H4HCRTR1HCRTR2 | |
| SCHEMBL7729688 | 0.87 | TSHR (0.36) | TSHREPHX2NR1H4HCRTR1HCRTR2 | |
| SCHEMBL7735461 | 0.87 | HDAC3 (0.36) | TSHREPHX2NR1H4HCRTR1HCRTR2 | |
| SCHEMBL7730268 | 0.87 | TSHR (0.49) | TSHREPHX2NR1H4ALDH1A1PDE2A | |
| SCHEMBL7731681 | 0.87 | TSHR (0.49) | TSHREPHX2NR1H4ALDH1A1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |