Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730988 | 0.91 | PDE2A (0.33) | PPARDPPARATSHRPDE2AHCRTR1 | |
| SCHEMBL7735446 | 0.90 | PPARD (0.32) | PPARDPPARATSHRPDE2AHCRTR1 | |
| SCHEMBL7729773 | 0.90 | TSHR (0.40) | PPARDPPARATSHRPDE2AHCRTR1 | |
| SCHEMBL7733408 | 0.88 | PPARG (0.32) | PPARDPPARATSHRPDE2A | |
| SCHEMBL7730668 | 0.88 | MAOB (0.33) | TSHRPDE2A | |
| SCHEMBL7732500 | 0.88 | HDAC3 (0.33) | PPARDPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL7722918 | 0.87 | HDAC3 (0.33) | PPARDPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL7729328 | 0.87 | PDE2A (0.32) | PDE2A | |
| SCHEMBL7731008 | 0.87 | TSHR (0.35) | PPARDPPARATSHRPDE2AHCRTR1 | |
| SCHEMBL7730665 | 0.86 | PRMT6 (0.38) | PPARDPPARATSHRKIF11MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |