Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735331 | 0.97 | KIF11 (0.33) | TSHREPHX2NR1H4PDE2AMAOB | |
| SCHEMBL16258067 | 0.93 | MAOB (0.34) | TSHRPDE2AMAOBSERPINE1KIF11 | |
| SCHEMBL7730202 | 0.90 | DAO (0.36) | TSHREPHX2NR1H4ALDH1A1MAOB | |
| SCHEMBL7735122 | 0.89 | TSHR (0.32) | TSHREPHX2NR1H4MAOBEPHX1 | |
| SCHEMBL7730668 | 0.89 | MAOB (0.33) | TSHRPDE2AMAOB | |
| SCHEMBL7733542 | 0.88 | MAOB (0.35) | TSHRALDH1A1MAOBSLC6A4 | |
| SCHEMBL7730683 | 0.88 | TSHR (0.35) | TSHREPHX2NR1H4PDE2AALDH1A1 | |
| SCHEMBL7729773 | 0.87 | TSHR (0.40) | TSHREPHX2NR1H4PDE2AALDH1A1 | |
| SCHEMBL7735170 | 0.87 | TSHR (0.44) | TSHREPHX2NR1H4ALDH1A1MAOB | |
| SCHEMBL14749515 | 0.87 | TSHR (0.44) | TSHREPHX2NR1H4ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |