SCHEMBL7729792

SCHEMBL7729792

C=CCC1=CCC(C(=O)O)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
ALOX15 P16050 2/20 0.42
CYP1B1 Q16678 1/20 0.42
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
TRPA1 O75762 1/20 0.35
KDM4E B2RXH2 1/20 0.34
RAB9A P51151 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRR1 P24046 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22571271 0.82 ALDH1A1 (0.43) ALDH1A1ALOX15CYP1B1TSHRLMNA
SCHEMBL12186689 0.79 ALDH1A1 (0.61) ALDH1A1ALOX15CYP1B1TSHRLMNA
SCHEMBL10626320 0.77 ALDH1A1 (0.46) ALDH1A1ALOX15CYP1B1TSHRLMNA
SCHEMBL28816571 0.77 ALDH1A1 (0.42) ALDH1A1ALOX15CYP1B1TSHRLMNA
SCHEMBL2222691 0.77 ALDH1A1 (0.46) ALDH1A1ALOX15CYP1B1TSHRLMNA
SCHEMBL7737508 0.75 ALOX15 (0.36) ALDH1A1ALOX15CYP1B1
SCHEMBL10623462 0.75 ALDH1A1 (0.44) ALDH1A1ALOX15CYP1B1TSHRLMNA
SCHEMBL10626341 0.74 ALOX15 (0.32) ALDH1A1ALOX15CYP1B1
SCHEMBL29510236 0.73 ALDH1A1 (0.42) ALDH1A1ALOX15CYP1B1TSHRLMNA
SCHEMBL18600640 0.72 STAT3 (0.42) ALDH1A1ALOX15CYP1B1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413448-B1 ESTERS; DOPANTS; LONGER CHIRAL SMECTIC PHASE PITCH; HIGHER TILT ANGLE; LOWER VISCOSITY; CRYSTALLIZATION SUPPRESSION; IMPROVED SOLUBILITY; BROADER C* PHASE TEMPERATURE RANGE DISPLAYTECH, INC. 2002-07-02 US disclosed
WO-2000065801-A9 CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE DISPLAYTECH INC (US) 2001-04-12 WO disclosed
WO-2000065801-A1 CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE DISPLAYTECH, INC. (US) 2000-11-02 WO disclosed
US-4786332-A TOBACCO PRODUCTS GIVAUDAN CORPORATION (US) 1988-11-22 US disclosed
EP-0110362-B1 FRAGRANCE AND FLAVOUR COMPOSITIONS L. GIVAUDAN & CIE Société Anonyme (CH) 1988-04-20 EP disclosed
US-4606925-A Flavoring with alkyl-substituted cyclohexyl and cyclohexenyl carboxylic acids GIVAUDAN CORPORATION (US) 1986-08-19 US disclosed
EP-0110362-A2 Fragrance and flavour compositions L. GIVAUDAN & CIE Société Anonyme (CH) 1984-06-13 EP disclosed