Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729792 | 0.72 | ALDH1A1 (0.42) | TSHRKMT2ALMNAALDH1A1ALOX15 | |
| SCHEMBL7469332 | 0.68 | POLB (0.66) | STAT3POLBTSHRSIGMAR1KMT2A | |
| SCHEMBL9795281 | 0.67 | TSHR (0.57) | STAT3POLBTSHRSIGMAR1KMT2A | |
| SCHEMBL9795287 | 0.67 | TSHR (0.57) | STAT3POLBTSHRSIGMAR1KMT2A | |
| SCHEMBL2325837 | 0.66 | GNAI3 (0.59) | STAT3POLBTSHRSIGMAR1KMT2A | |
| Oxalic Acid SCHEMBL9795105 | 0.64 | POLB (0.53) | STAT3POLBTSHRSIGMAR1KMT2A | |
| SCHEMBL12820426 | 0.64 | POLB (0.53) | STAT3POLBTSHRSIGMAR1KMT2A | |
| SCHEMBL20670372 | 0.64 | TSHR (0.50) | STAT3POLBTSHRSIGMAR1KMT2A | |
| Oxalic Acid SCHEMBL9795121 | 0.64 | POLB (0.53) | STAT3POLBTSHRSIGMAR1KMT2A | |
| SCHEMBL22498221 | 0.64 | BRD4 (0.35) | TSHRKMT2ALMNAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3138834-B1 | CYCLOHEXENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | HYUNDAI PHARM CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |
| EP-3138834-A1 | CYCLOHEXENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | Hyundai Pharm Co., Ltd. (KR) | 2017-03-08 | — | — | EP | disclosed |