Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | NRP1 | O14786 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731387 | 0.93 | ALPL (0.34) | DAOTRPV4DHODHMAOB | |
| SCHEMBL7732816 | 0.91 | TRPV4 (0.36) | CYP2A6TRPV4DHODHTSHREPHX2 | |
| SCHEMBL7734975 | 0.91 | TSHR (0.34) | DAOTRPV4TSHR | |
| SCHEMBL7730411 | 0.90 | HSD17B10 (0.39) | TSHRSLC6A4SLC6A3 | |
| SCHEMBL7731469 | 0.88 | PPARA (0.34) | CYP2A6TRPV4DHODH | |
| SCHEMBL7730572 | 0.88 | TRPV4 (0.33) | DAOCYP2A6TRPV4GPR84DHODH | |
| SCHEMBL7733182 | 0.87 | DAO (0.33) | DAOTRPV4GPR84DHODHMAOB | |
| SCHEMBL7730247 | 0.87 | DAO (0.40) | DAOTRPV4MAOB | |
| SCHEMBL7733192 | 0.86 | ALPL (0.34) | TRPV4DHODHMAOB | |
| SCHEMBL7730202 | 0.86 | DAO (0.36) | DAOGPR84TAAR1MAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |