Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722882 | 0.93 | DAO (0.40) | DAOTRPV4CYP11B1CYP11B2RORC | |
| SCHEMBL7735351 | 0.91 | TRPV4 (0.39) | TRPV4CYP11B1CYP11B2ARMAOB | |
| SCHEMBL7732553 | 0.91 | DAO (0.39) | DAOTRPV4CYP11B1CYP11B2RORC | |
| SCHEMBL7729846 | 0.90 | DAO (0.38) | DAOTRPV4CYP11B1CYP11B2RORC | |
| SCHEMBL7730381 | 0.87 | DAO (0.33) | DAOTRPV4MAOB | |
| SCHEMBL7733482 | 0.87 | AR (0.39) | DAOTRPV4CYP11B1CYP11B2AR | |
| SCHEMBL7732790 | 0.85 | NPC1 (0.37) | DAOTRPV4CYP11B1CYP11B2AR | |
| SCHEMBL7731592 | 0.84 | TSHR (0.39) | TRPV4CYP11B1CYP11B2AR | |
| SCHEMBL6665018 | 0.83 | DAO (0.39) | DAOTRPV4CYP11B1CYP11B2RORC | |
| SCHEMBL7730202 | 0.82 | DAO (0.36) | DAOMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |