Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729128 | 0.96 | THRB (0.40) | S1PR1THRBPPARAPPARGHTR2A | |
| SCHEMBL7735067 | 0.92 | DAO (0.36) | S1PR1S1PR3THRBPPARAPPARG | |
| SCHEMBL7734936 | 0.92 | THRB (0.36) | THRBDAOCETP | |
| SCHEMBL7733314 | 0.90 | RARB (0.36) | S1PR1S1PR3PPARAPPARGRARB | |
| SCHEMBL7730235 | 0.90 | S1PR1 (0.36) | S1PR1S1PR3THRBPPARAPPARG | |
| SCHEMBL7722674 | 0.90 | S1PR1 (0.36) | S1PR1S1PR3THRBPPARAPPARG | |
| SCHEMBL7722585 | 0.89 | DAO (0.36) | DAO | |
| SCHEMBL7732239 | 0.89 | NPC1 (0.33) | S1PR1S1PR3CA1CA2 | |
| SCHEMBL7731647 | 0.89 | S1PR1 (0.31) | S1PR1S1PR3 | |
| SCHEMBL7722843 | 0.89 | DAO (0.36) | S1PR1S1PR3THRBPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |