SCHEMBL7734936

SCHEMBL7734936

CCCc1cc(F)c(C(F)(F)Oc2ccc(CCc3cc(F)c(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
DAO P14920 2/20 0.34
MAOB P27338 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32
TUBB2B Q9BVA1 1/20 0.32
TUBB1 Q9H4B7 1/20 0.32
SENP8 Q96LD8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7730403 0.92 S1PR1 (0.36) THRBDAOCETP
SCHEMBL7722585 0.92 DAO (0.36) DAOMAOBGPR84TUBB4ATUBB
SCHEMBL7730459 0.92 DAO (0.38) THRBDAOMAOBGPR84TUBB4A
SCHEMBL7729128 0.91 THRB (0.40) THRBALDH1A1SLC6A4SLC6A3KMT2A
SCHEMBL7732784 0.89 RARB (0.33) MAOBRAB9ANPC1SMN1; SMN2
SCHEMBL7730013 0.89 THRB (0.36) THRBDAOMAOBSENP8SENP7
SCHEMBL7730393 0.89 MAOB (0.34) THRBDAOMAOBGPR84TUBB4A
SCHEMBL7722746 0.88 MAOB (0.31) DAOMAOB
SCHEMBL7732810 0.88 DAO (0.37) THRBDAOGPR84TUBB4ATUBB
SCHEMBL7729113 0.88 MAOB (0.32) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed