Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | MEN1 | O00255 | 11/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.52 |
| ▸ | POLB | P06746 | 10/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Furfurylidene-P-Anisidine SCHEMBL7735571 | 0.81 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2APOLB | |
| N-Furfurylidene-P-Anisidine SCHEMBL11377145 | 0.81 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30380017 | 0.81 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3031551 | 0.77 | POLB (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3031548 | 0.77 | POLB (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3031546 | 0.77 | POLB (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8952516 | 0.75 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL22340707 | 0.75 | TRPA1 (0.59) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10662429 | 0.75 | TRPA1 (0.59) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7731715 | 0.75 | TRPA1 (0.59) | MAPTALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690856-B1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | UNIV NEW YORK STATE RES FOUND (US) | 2002-12-04 | — | — | EP | disclosed |
| US-5705508-A | FORMING TAXOL DERIVATIVES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-01-06 | — | — | US | disclosed |
| US-5599820-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-02-04 | — | — | US | disclosed |
| US-5475011-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-12-12 | — | — | US | disclosed |