Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | CTSC | P53634 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723456 | 0.81 | CTSS (0.41) | CTSSLMNAMAPTF2CTSC | |
| SCHEMBL21436502 | 0.81 | CTSS (0.41) | CTSSLMNAMAPTF2CTSC | |
| SCHEMBL7733530 | 0.81 | CTSS (0.41) | CTSSLMNAMAPTF2CTSC | |
| SCHEMBL7733118 | 0.81 | CTSS (0.41) | CTSSLMNAMAPTF2CTSC | |
| SCHEMBL7733537 | 0.81 | CTSS (0.41) | CTSSLMNAMAPTF2CTSC | |
| SCHEMBL7733137 | 0.81 | CTSS (0.41) | CTSSLMNAMAPTF2CTSC | |
| SCHEMBL5018348 | 0.66 | FAAH (0.37) | LMNAMAPTCTSCXDHPRSS8 | |
| SCHEMBL7728351 | 0.65 | CTSS (0.44) | CTSSF2CTSCMASP2 | |
| SCHEMBL21436251 | 0.64 | F2 (0.35) | CTSSF2CTSCMASP2 | |
| SCHEMBL21436586 | 0.63 | F2 (0.37) | CTSSF2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |