Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 3/20 | 0.32 |
| ▸ | HIPK1 | Q86Z02 | 3/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.32 |
| ▸ | HIPK3 | Q9H422 | 3/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126375 | 0.77 | ALDH1A1 (0.54) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL361847 | 0.77 | KDM4E (0.50) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL30284405 | 0.77 | KDM4E (0.50) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL2517095 | 0.74 | KDM4E (0.45) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL8881998 | 0.73 | KDM4E (0.46) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL7731743 | 0.72 | KDM4E (0.41) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL9251027 | 0.70 | MAPT (0.40) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL9056690 | 0.70 | KDM4E (0.44) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL8681140 | 0.70 | ALDH1A1 (0.49) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL5615321 | 0.70 | SMN1; SMN2 (0.43) | KDM4EMEN1NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6478988-B1 | Photochromic substituted naphthopyran compounds | BMC VISION-EASE LENS, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1016702-A2 | Photochromic substituted naphthopyran compounds | BMC Vision-Ease Lens Inc. (US) | 2000-07-05 | — | — | EP | disclosed |