Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789398 | 0.79 | ALDH1A1 (0.59) | ALDH1A1ADRA2BPTGS1TDP1HSD17B10 | |
| SCHEMBL4965452 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ADRA2BPTGS1TDP1HSD17B10 | |
| SCHEMBL25135312 | 0.76 | KDM4E (0.47) | ALDH1A1ADRA2BPTGS1TDP1HSD17B10 | |
| SCHEMBL3793754 | 0.75 | ALDH1A1 (0.63) | ALDH1A1ADRA2BPTGS1TDP1HSD17B10 | |
| SCHEMBL3789240 | 0.74 | NCOA1 (0.49) | ALDH1A1HSD17B10GAALMNACYP1A2 | |
| SCHEMBL5754263 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TDP1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL3789543 | 0.72 | KDM4E (0.50) | ALDH1A1PTGS1TDP1HSD17B10KDM4E | |
| SCHEMBL7731913 | 0.72 | ALDH1A1 (0.52) | ALDH1A1ADRA2BPTGS1TDP1HSD17B10 | |
| SCHEMBL25135315 | 0.70 | NCOA1 (0.62) | ALDH1A1TDP1HSD17B10SMN1; SMN2GAA | |
| SCHEMBL3786516 | 0.70 | APP (0.56) | TDP1SMN1; SMN2GAAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6364465-B1 | PRIOR TO IMAGING TO FORM SAID INK PASSAGEWAYS, COMPRISES AN UNSATURATED COMPOUND, A PHOTOINITIATOR, AND THE POLY(AMIC ACID) PREPARED FROM AT LEAST ONE DIANHYDRIDE AND AT LEAST ONE ALIPHATIC DIAMINE. | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-04-02 | — | — | US | disclosed |