Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GOT1 | P17174 | 5/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607154 | 0.88 | DRD2 (0.54) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL7605695 | 0.84 | CACNA1G (0.42) | DRD2DRD3DRD4MAPTKMT2A | |
| SCHEMBL6935596 | 0.80 | CACNA1G (0.51) | DRD2DRD3MAPTKMT2AHTR1A | |
| SCHEMBL7554379 | 0.79 | DRD2 (0.67) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL6931647 | 0.77 | GAA (0.55) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL7613963 | 0.77 | DRD3 (0.50) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL6194887 | 0.75 | GOT1 (0.44) | DRD2DRD3DRD4GAAMAPT | |
| SCHEMBL6772142 | 0.71 | MAPT (0.59) | DRD2DRD3MAPTADRB1MEN1 | |
| SCHEMBL6930796 | 0.70 | DRD2 (0.59) | DRD2DRD3DRD4MAPTADRB1 | |
| SCHEMBL6778522 | 0.69 | MAPT (0.65) | DRD2DRD3DRD4GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | claimed |
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |