Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611161 | 1.00 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL11403376 | 1.00 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL1610894 | 1.00 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL7732435 | 1.00 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL1119421 | 1.00 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL1119390 | 0.98 | IGF1R (0.53) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL1119426 | 0.91 | CYP1A2 (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL22092404 | 0.88 | CYP1A2 (0.50) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL10571160 | 0.88 | IGF1R (0.61) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL6546754 | 0.85 | IGF1R (0.64) | IGF1RALOX15CYP1A2CYP2A6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565865-A | ANTITUMOR AGENTS, MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-01-21 | — | — | US | claimed |
| EP-0061872-B1 | ETHYLENEGLYCOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-08-07 | — | — | EP | claimed |
| EP-0040039-B1 | ETHYLENE GLYCOL DERIVATIVES OF AMMONIOETHYL PHOSPHATE, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-08-01 | — | — | EP | claimed |
| EP-0035375-B1 | CARBAMIC ACID ESTERS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1983-08-10 | — | — | EP | claimed |
| US-20050152959-A1 | Use of a lysolipid for the preparation of a composition for transfection of a polynucleotide into a cell | TRANSGENE S. A. (FR) | 2005-07-14 | — | — | US | disclosed |
| US-20050112187-A1 | Combination product intended for carrying out a cytotoxic treatment, in particular an antitumour treatment, in a mammal | TRANSGENE S.A. (FR) | 2005-05-26 | — | — | US | disclosed |
| EP-1465597-A2 | USE OF A LYSOLIPID FOR THE PREPARATION OF A COMPOSITION FOR TRANSFECTION OF A POLYNUCLEOTIDE INTO A CELL | TRANSGENE S.A. (FR) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003052095-A2 | USE OF A LYSOLIPID FOR THE PREPARATION OF A COMPOSITION FOR TRANSFECTION OF A POLYNUCLEOTIDE INTO A CELL | TRANSGENE S.A. (FR) | 2003-06-26 | — | — | WO | disclosed |
| US-20020025941-A1 | Combination product intended for carrying out a cytotoxic treatment, in particular an antitumour treatment, in a mammal | TRANSGENE S.A. (FR) | 2002-02-28 | — | — | US | disclosed |
| US-4935520-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4565865-A | ANTITUMOR AGENTS, MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-01-21 | — | — | US | disclosed |
| US-4551532-A | MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-11-05 | — | — | US | disclosed |
| US-4542219-A | ANTITUMOR, AGRICULTURAL FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-09-17 | — | — | US | disclosed |
| EP-0061872-B1 | ETHYLENEGLYCOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-08-07 | — | — | EP | disclosed |
| EP-0108565-A2 | Phospholipids, their production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1984-05-16 | — | — | EP | disclosed |
| US-4408052-A | FUNGICIDES AND ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| EP-0035375-B1 | CARBAMIC ACID ESTERS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1983-08-10 | — | — | EP | disclosed |
| EP-0061872-A1 | Ethyleneglycol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-10-06 | — | — | EP | disclosed |
| EP-0040039-A1 | Ethylene glycol derivatives of ammonioethyl phosphate, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-11-18 | — | — | EP | disclosed |
| EP-0035375-A1 | Carbamic acid esters, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050152959-A1 | Use of a lysolipid for the preparation of a composition for transfection of a polynucleotide into a cell | LPCAT1, LPCAT3, LCLAT1 | IGF1R 4757/4885ALOX15 771/4885CYP1A2 4868/4885 |
| US-20050112187-A1 | Combination product intended for carrying out a cytotoxic treatment, in particular an antitumour treatment, in a mammal | TYMP, PHOSPHO1, PIGS | IGF1R 3528/4885ALOX15 1846/4885CYP1A2 4831/4885 |
| US-20020025941-A1 | Combination product intended for carrying out a cytotoxic treatment, in particular an antitumour treatment, in a mammal | TYMP, PHOSPHO1, PIGS | IGF1R 3528/4885ALOX15 1846/4885CYP1A2 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.