SCHEMBL1611161

SCHEMBL1611161

[CH2]CCCCCCc1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.52
ALOX15 P16050 1/20 0.52
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
HRH1 P35367 1/20 0.47
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
CHRM2 P08172 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11403376 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1610894 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL6317614 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL7732435 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1119421 1.00 IGF1R (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1119390 0.98 IGF1R (0.53) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL1119426 0.91 CYP1A2 (0.52) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL22092404 0.88 CYP1A2 (0.50) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL10571160 0.88 IGF1R (0.61) IGF1RALOX15CYP1A2CYP2A6TAAR1
SCHEMBL6546754 0.85 IGF1R (0.64) IGF1RALOX15CYP1A2CYP2A6TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116699034-A Rapid identification method for new structure of mental active substance of fentanyl 广西大学 2023-09-05 CN disclosed
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 US disclosed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-5432267-A Inhibits tumor necrosis factor derivation by endotoxin DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1995-07-11 US disclosed
EP-0563908-A1 Amino sugar derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-10-06 EP disclosed
EP-0143385-B1 PHOSPHORYLISED GLYCOSIL AMIDES, UREAS, CARBAMATES AND THIOCARBAMATES, METHOD FOR THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1989-03-15 EP disclosed
US-4686208-A Phosphorylated glycosyl-amides, -ureas, -carbamates and -thiocarbamates and method of use BAYER AKTIENGESELLSCHAFT (DE) 1987-08-11 US disclosed
EP-0143385-A2 Phosphorylised glycosil amides, ureas, carbamates and thiocarbamates, method for their preparation and their use BAYER AG (DE) 1985-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 IGF1R 684/4885ALOX15 1511/4885CYP1A2 125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.