Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737512 | 0.78 | RXFP1 (0.33) | L3MBTL1ALDH1A1LMNANR1H2NR1H3 | |
| SCHEMBL7732407 | 0.76 | NR1H2 (0.36) | MAOBKDM4ERAB9ANPC1L3MBTL1 | |
| Benzene SCHEMBL7542715 | 0.72 | KMT2A (0.46) | PTPN1MAOAMAOBMEN1KMT2A | |
| SCHEMBL10913604 | 0.71 | ALDH1A1 (0.39) | ALDH1A1NR1H2NR1H3TSHR | |
| SCHEMBL29786760 | 0.71 | KMT2A (0.61) | PTPN1MAOAMAOBMEN1KMT2A | |
| SCHEMBL982388 | 0.71 | KMT2A (0.61) | PTPN1MAOAMAOBMEN1KMT2A | |
| SCHEMBL6402708 | 0.68 | MEN1 (0.38) | PTPN1MAOAMAOBMEN1KMT2A | |
| SCHEMBL10941267 | 0.67 | NR1H2 (0.38) | RAB9ANPC1ALDH1A1SMN1; SMN2NR1H2 | |
| SCHEMBL2003493 | 0.67 | APOBEC3G (0.38) | MAOBALDH1A1NR1H2NR1H3 | |
| SCHEMBL3700317 | 0.66 | NR1H2 (0.37) | ALDH1A1LMNABLMNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |