Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700317 | 0.79 | NR1H2 (0.37) | ALDH1A1NR1H2NR1H3LMNA | |
| SCHEMBL7732407 | 0.79 | NR1H2 (0.36) | NR1H2NR1H3LMNAL3MBTL1 | |
| SCHEMBL7732437 | 0.78 | PTPN1 (0.35) | ALDH1A1POLBNR1H2NR1H3LMNA | |
| SCHEMBL5012176 | 0.74 | RXFP1 (0.40) | RXFP1ALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL10941267 | 0.69 | NR1H2 (0.38) | ALDH1A1NR1H2NR1H3 | |
| SCHEMBL10913604 | 0.69 | ALDH1A1 (0.39) | ALDH1A1NR1H2NR1H3 | |
| SCHEMBL2003493 | 0.69 | APOBEC3G (0.38) | ALDH1A1NR1H2NR1H3 | |
| SCHEMBL18796002 | 0.68 | NR1H2 (0.37) | ALDH1A1NR1H2NR1H3 | |
| SCHEMBL1147728 | 0.66 | NR1H2 (0.53) | ALDH1A1NR1H2NR1H3L3MBTL1 | |
| SCHEMBL31656346 | 0.66 | ALDH1A1 (0.38) | RXFP1ALDH1A1POLBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |