SCHEMBL7732487

SCHEMBL7732487

CCc1ccc(C(F)(F)Oc2ccc(CCc3cc(F)c(OC(F)(F)F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.39
GPR84 Q9NQS5 1/20 0.38
TSHR P16473 1/20 0.36
FFAR4 Q5NUL3 3/20 0.36
SLC6A4 P31645 4/20 0.36
SLC6A3 Q01959 4/20 0.36
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35
TUBA3E Q6PEY2 1/20 0.35
TUBA1A Q71U36 1/20 0.35
TUBA1C Q9BQE3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7728636 0.91 DAO (0.36) DAOGPR84TSHRFFAR4SLC6A4
SCHEMBL7731627 0.90 PDE2A (0.34) TSHRFFAR4PPARDPPARAALDH1A1
SCHEMBL7732511 0.89 PPARG (0.35) DAOGPR84TSHRFFAR4SLC6A4
SCHEMBL7734971 0.89 PRMT6 (0.39) TSHRFFAR4PPARDPPARA
SCHEMBL7722606 0.88 DAO (0.36) DAOGPR84TSHRFFAR4SLC6A4
SCHEMBL7730923 0.88 S1PR1 (0.35) DAOGPR84PPARAALOX5PPARG
SCHEMBL7729295 0.88 TSHR (0.35) TSHRPPARDPPARAALDH1A1BCHE
SCHEMBL7729345 0.87 FFAR4 (0.32) DAOGPR84FFAR4TUBB4ATUBB
SCHEMBL7731389 0.86 DAO (0.36) DAOGPR84TSHRFFAR4SLC6A4
SCHEMBL7734959 0.86 DAO (0.40) DAOGPR84TSHRFFAR4SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed