Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730937 | 0.91 | CYP11B1 (0.37) | PRMT6CYP11B1CYP11B2KIF11TSHR | |
| SCHEMBL7732487 | 0.89 | DAO (0.39) | TSHRPPARAPPARDFFAR4 | |
| SCHEMBL7731319 | 0.89 | KIF11 (0.40) | PRMT6CYP11B1CYP11B2KIF11TSHR | |
| SCHEMBL7731627 | 0.89 | PDE2A (0.34) | KIF11TSHRPPARAGRM2PPARD | |
| SCHEMBL7729149 | 0.89 | RARB (0.36) | PRMT6CYP11B1CYP11B2KIF11PPARA | |
| SCHEMBL7729079 | 0.88 | KIF11 (0.43) | PRMT6CYP11B1CYP11B2KIF11PPARA | |
| SCHEMBL7735516 | 0.88 | RARB (0.40) | PRMT6CYP11B1CYP11B2KIF11TSHR | |
| SCHEMBL7723050 | 0.87 | KIF11 (0.36) | PRMT6CYP11B1CYP11B2KIF11FFAR4 | |
| SCHEMBL7729295 | 0.87 | TSHR (0.35) | TSHRPPARAPPARD | |
| SCHEMBL7722612 | 0.85 | PRMT6 (0.38) | PRMT6KIF11TSHRPPARAAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |