SCHEMBL7722606

SCHEMBL7722606

CCc1ccc(C(F)(F)Oc2ccc(CCc3cc(F)c(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.36
GPR84 Q9NQS5 1/20 0.34
TSHR P16473 1/20 0.33
SLC6A4 P31645 4/20 0.33
SLC6A3 Q01959 4/20 0.33
FFAR1 O14842 1/20 0.33
MAOB P27338 2/20 0.33
FFAR4 Q5NUL3 2/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31
TUBA1A Q71U36 1/20 0.31
TUBA1C Q9BQE3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7729833 0.91 DAO (0.34) DAOGPR84TSHRFFAR1MAOB
SCHEMBL7731389 0.90 DAO (0.36) DAOGPR84TSHRSLC6A4SLC6A3
SCHEMBL7735237 0.89 FFAR1 (0.33) DAOTSHRFFAR1MAOBP2RX7
SCHEMBL14749512 0.89 TSHR (0.38) TSHRSLC6A4FFAR1FFAR4TAAR1
SCHEMBL7732487 0.88 DAO (0.39) DAOGPR84TSHRSLC6A4SLC6A3
SCHEMBL7735124 0.88 S1PR1 (0.37) DAOALOX5PPARG
SCHEMBL7731319 0.88 KIF11 (0.40) TSHRFFAR1MAOB
SCHEMBL7729099 0.87 HTR2A (0.37) SLC6A4SLC6A3ALDH1A1PPARG
SCHEMBL7735122 0.87 TSHR (0.32) TSHRFFAR1MAOBP2RX7
SCHEMBL7733182 0.86 DAO (0.33) DAOGPR84TSHRSLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed