Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863993 | 0.78 | HTT (0.40) | CYP1A2IDO1TDO2ALDH1A1HTT | |
| SCHEMBL1167742 | 0.78 | CYP1A2 (0.59) | CYP1A2ALDH1A1HIF1ACYP2C9CYP2C19 | |
| SCHEMBL3944521 | 0.78 | GABRA1 (0.43) | CYP1A2ALDH1A1HPGDHIF1ALMNA | |
| SCHEMBL25308183 | 0.78 | GABRA1 (0.43) | CYP1A2ALDH1A1HPGDHIF1ALMNA | |
| SCHEMBL23674864 | 0.73 | GSR (0.38) | CYP1A2IDO1TDO2ALDH1A1HPGD | |
| SCHEMBL27937647 | 0.72 | HTT (0.43) | CYP1A2IDO1TDO2ALDH1A1HPGD | |
| SCHEMBL446453 | 0.71 | CES2 (0.43) | CYP1A2ALDH1A1HPGDHIF1ALMNA | |
| SCHEMBL23496048 | 0.70 | GSR (0.35) | CYP1A2ALDH1A1HPGDHTTLMNA | |
| SCHEMBL23496050 | 0.70 | GSR (0.35) | CYP1A2ALDH1A1HPGDHTTLMNA | |
| Bromide SCHEMBL29163778 | 0.70 | NPC1 (0.42) | CYP1A2ALDH1A1HPGDHIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407083-B1 | ADMINISTERING AS 7-NITROBENZISOSELENAZOLINE DERIVATIVES AS ANTITUMOR AND ANTICARCINOGENIC AGENTS | OXIS INTERNATIONAL, INC. | 2002-06-18 | — | — | US | disclosed |
| US-6130212-A | ANTITUMOR | OXIS INTERNATIONAL S.A. (US) | 2000-10-10 | — | — | US | disclosed |
| US-6057310-A | TREATING LEUKEMIA, BREAST CANCER | OXIS ISLE OF MAN, LIMITED (US) | 2000-05-02 | — | — | US | disclosed |
| US-6001825-A | Use of novel organoselenium compounds as pro-oxidizing agents their methods of preparation and pharmaceutical compositions and application thereof | OXIS ISLE OF MAN, LIMITED (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0819682-A1 | Use of novel organoselenium compounds as pro-oxidizing agents, their methods of preparation and pharmaceutical compositions and application containing them | Oxis International S.A. (FR) | 1998-01-21 | — | — | EP | disclosed |