Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689177 | 0.83 | CSNK2A2 (0.54) | ABCG2CSNK2A2CSNK2BCSNK2A1HTT | |
| SCHEMBL13145555 | 0.77 | BRD4 (0.46) | CSNK2A2CSNK2BCSNK2A1HTTSMN1; SMN2 | |
| SCHEMBL11275611 | 0.75 | BRD4 (0.57) | ABCG2CSNK2A2CSNK2BCSNK2A1HTT | |
| SCHEMBL13632224 | 0.74 | ABCG2 (0.55) | ABCG2CSNK2A2CSNK2BCSNK2A1HTT | |
| SCHEMBL7685208 | 0.68 | MAP1LC3B (0.44) | ABCG2CSNK2A2CSNK2BCSNK2A1BRD4 | |
| Ethoxycarbonyl Group SCHEMBL27990767 | 0.66 | ALDH1A1 (0.38) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL7740430 | 0.66 | SMN1; SMN2 (0.43) | ABCG2CSNK2A2CSNK2BCSNK2A1SMN1; SMN2 | |
| SCHEMBL12951913 | 0.65 | F2 (0.44) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL10514049 | 0.64 | ABCG2 (0.38) | ABCG2CSNK2A2CSNK2BCSNK2A1SMN1; SMN2 | |
| SCHEMBL22916957 | 0.64 | TP53 (0.50) | HTTSMN1; SMN2KDM4ETP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407261-B1 | OXIDIZING THE CORRESPONDING KETONE COMPOUND BY HEATING WITH A SUKFINATING COMPOUND | ELI LILLY AND COMPANY | 2002-06-18 | — | — | US | disclosed |