SCHEMBL7732887

SCHEMBL7732887

CCCC1(O)CCC(C)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 3/20 0.33
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32
ESR2 Q92731 2/20 0.31
HSD17B3 P37058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21134598 1.00 SLC6A4 (0.33) SLC6A4SLC6A3KDM4EPKMESR2
SCHEMBL21134592 1.00 SLC6A4 (0.33) SLC6A4SLC6A3KDM4EPKMESR2
SCHEMBL8074193 0.86 OPRM1 (0.39) KDM4EPKMHSD17B3
SCHEMBL13213903 0.83 OPRM1 (0.42) HSD17B3
SCHEMBL9815873 0.81 SHBG (0.33) SLC6A4SLC6A3ESR2HSD17B3
SCHEMBL3012888 0.80 KDM4E (0.34) KDM4EPKMESR2
SCHEMBL17835264 0.80 KDM4E (0.34) KDM4EPKMESR2
SCHEMBL17706160 0.80 KDM4E (0.34) KDM4EPKMESR2
SCHEMBL129415 0.79
SCHEMBL9840935 0.76 ALDH1A1 (0.33) SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170253576-A1 HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-09-07 US disclosed
EP-1632483-B1 HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS AVENTIS PHARMA INC (US) 2008-10-29 EP disclosed
US-6410748-B1 Alicycli c group-containing monomer KABUSHIKI KAISHA TOSHIBA (JP) 2002-06-25 US disclosed
US-6291129-B1 LIGHT SENSITIVE ELEMENT WITH UNSATURATED POLYMERS KABUSHIKI KAISHA TOSHIBA (JP) 2001-09-18 US disclosed
US-6004719-A ACID-GENERATING LAYER OR PHASE COMPRISING A MIXTURE OF A SUPERACID PRECURSOR, A SENSITIZING DYE AND A SECONDARY ACID GENERATOR, AND A COLOR-CHANGE LAYER OR PHASE COMPRISING AN IMAGE DYE. POLAROID CORPORATION (US) 1999-12-21 US disclosed
EP-0757629-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1999-01-20 EP disclosed
EP-0757628-B1 PROCESS FOR FIXING AN IMAGE POLAROID CORP (US) 1998-12-02 EP disclosed
EP-0665960-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1998-08-19 EP disclosed
US-5631118-A MULTILAYER ELEMENT WITH ACID GENERATING LAYER, ACID PRECURSOR, SENSITIZING DYE, ACID GENERATOR AND COLOR CHANGING LAYER POLAROID CORPORATION (US) 1997-05-20 US disclosed
EP-0757629-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1997-02-12 EP disclosed
WO-1995029068-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1995-11-02 WO disclosed
WO-1995029067-A1 PROCESS FOR FIXING AN IMAGE POLAROID CORPORATION (US) 1995-11-02 WO disclosed
US-5453345-A Imaging medium POLAROID CORPORATION (US) 1995-09-26 US disclosed
US-5445917-A Superacid precursor to catalyze thermal decomposition of secondary acid generator, such as squaric acid and oxalic acid derivatives; effecting color change in imaging process POLAROID CORPORATION (US) 1995-08-29 US disclosed
US-5441850-A Exposing medium to actinic radiation in specified wavelength so sensitizing dye decomposes superacid precursor, heating to decompose secondary acid generator, mixing acid generating and color change layers to form image, providing base to restore POLAROID CORPORATION (US) 1995-08-15 US disclosed
EP-0665961-A1 IMAGING MEDIUM AND PROCESS. POLAROID CORP (US) 1995-08-09 EP disclosed
EP-0665960-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1995-08-09 EP disclosed
US-5395736-A Exposing superoxide precursor to actinic radiation, generating superacid, mixing with oxalic acid diester, heating POLAROID CORPORATION (US) 1995-03-07 US disclosed
WO-1994010606-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO disclosed
WO-1994010607-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170253576-A1 HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS FNTB, SLC11A2, TBCD SLC6A4 3031/4885SLC6A3 1578/4885KDM4E 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.