SCHEMBL7733035

SCHEMBL7733035

C=CC(=O)OCCC[Si](O)(OCC)OCC

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.58
HPGD P15428 1/20 0.58
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HCAR2 Q8TDS4 4/20 0.35
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20572843 0.87 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL108297 0.87 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL18040479 0.85 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL20573063 0.85 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL7878189 0.85 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8899363 0.85 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL93561 0.85 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL107693 0.83 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8899031 0.83 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
Hydrogen Peroxide SCHEMBL28128571 0.83 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108602955-B Photocuring method, compound used in photocuring method, and composition 富士胶片和光纯药株式会社 2021-08-06 CN disclosed
US-10774062-B2 Photocuring method, compound and composition used therein FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-09-15 US disclosed
EP-3409709-B1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-08-19 EP disclosed
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-02-21 US disclosed
EP-3409709-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM Wako Pure Chemical Corporation (JP) 2018-12-05 EP disclosed
CN-108602955-A The compound and composition used in process for photocuring, the process for photocuring 富士胶片和光纯药株式会社 2018-09-28 CN disclosed
EP-0803542-B1 Electrically conductive silicone elastomer compositions and use for manufacturing semiconductor devices DOW CORNING TORAY SILICONE (JP) 2002-09-18 EP disclosed
US-6039831-A HYDROSILYLATION CURABLE ELECTROCONDUCTIVE SILICONE ELASTOMER HAVING AN ACRYLIC FUNCTIONAL GROUP CONTAINING POLYSILOXANE IS IRRADIATED WITH HIGH BEAM ENERGY TO CURE EXPOSED EDGES, PREVENTING MIGRATION OF LOW MOLECULARWEIGHT SILICONE SPECIES DOW CORNING TORAY SILICONE CO., LTD. (JP) 2000-03-21 US disclosed
US-5872170-A HYDROSILYLATION CURABLE ELECTRICALLY CONDUCTIVE SILICONE ELASTOMER COMPOSITION CONTAINING AN ACRYLIC FUNCTIONAL GROUP-CONTAINING ORGANOPOLYSILOXANE DOWN CORNING TORAY SILICONE CO., LTD. (JP) 1999-02-16 US disclosed
EP-0803542-A2 Electrically conductive silicone elastomer compositions and use for manufacturing semiconductor devices Dow Corning Toray Silicone Company Ltd. (JP) 1997-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN ESD, TMT1A, PAM TSHR 4741/4885HPGD 323/4885ALDH1A1 23/4885
US-10774062-B2 Photocuring method, compound and composition used therein ESD, TMT1A, PAM TSHR 4741/4885HPGD 323/4885ALDH1A1 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.