Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 4/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GRM6 | O15303 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732416 | 0.92 | NPSR1 (0.47) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL7734348 | 0.89 | AKR1C3 (0.53) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL27543805 | 0.87 | AKR1C3 (0.55) | ALDH1A1L3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL7723428 | 0.86 | ACP3 (0.48) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL27480183 | 0.86 | TSHR (0.48) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL7732581 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL9157996 | 0.80 | L3MBTL1 (0.62) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL28184959 | 0.80 | TSHR (0.48) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL9158002 | 0.80 | L3MBTL1 (0.62) | ALDH1A1TSHRL3MBTL1MEN1HPGD | |
| SCHEMBL7732979 | 0.78 | LMNA (0.47) | ALDH1A1L3MBTL1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |