SCHEMBL7733231

SCHEMBL7733231

CCN(c1ccc(N(CC)C(C)OC(C)(C)C)cc1)C(C)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 8/20 0.33
NR1H3 Q13133 8/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IGLV6-57 P01721 1/20 0.33
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733236 0.81 CACNA1F (0.33)
SCHEMBL7733707 0.77 NR1H2 (0.35) NR1H2NR1H3ALDH1A1LMNAMAPT
SCHEMBL7731814 0.75 LMNA (0.35) NR1H2NR1H3ALDH1A1LMNAMAPT
SCHEMBL7731802 0.72 ALDH1A1 (0.32) ALDH1A1LMNAHTT
SCHEMBL11580018 0.69 TDP1 (0.48) NR1H2NR1H3ALDH1A1LMNAMAPT
SCHEMBL12888007 0.69
SCHEMBL10444592 0.68 TP53 (0.39) NR1H2NR1H3ALDH1A1LMNAMAPT
SCHEMBL23789498 0.67
SCHEMBL10938398 0.67 ALDH1A1 (0.52) ALDH1A1LMNAMAPTL3MBTL1IGLV6-57
SCHEMBL10472027 0.67 TP53 (0.38) NR1H2NR1H3ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399272-B1 Phenylenediamine derivative-type additive useful for a chemically amplified photoresist HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-06-04 US disclosed