SCHEMBL7731464

SCHEMBL7731464

CCc1ccc(C(F)(F)Oc2ccc(-c3cc(F)c(OC(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.33
PPARA Q07869 2/20 0.33
PPARG P37231 1/20 0.33
SERPINE1 P05121 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
FFAR4 Q5NUL3 3/20 0.31
FFAR1 O14842 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
PDE2A O00408 1/20 0.30
GRM2 Q14416 1/20 0.30
TSHR P16473 1/20 0.30
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30
HCRTR1 O43613 2/20 0.30
HCRTR2 O43614 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733355 0.91 PDE2A (0.34) FFAR1PDE2ATSHRHCRTR1HCRTR2
SCHEMBL7731674 0.91 MAOB (0.33) PPARDPPARAPPARG
SCHEMBL7731988 0.89 PDE2A (0.33) FFAR1PDE2A
SCHEMBL7729471 0.89 RARB (0.37) PPARDPPARAPPARG
SCHEMBL7729451 0.88 FFAR4 (0.34) FFAR4PDE2ATSHRHCRTR1HCRTR2
SCHEMBL7731179 0.88 RARB (0.41) PPARAPPARGTSHR
SCHEMBL7731626 0.87 CYP17A1 (0.36) PPARDSERPINE1PRMT6FFAR1RXRA
SCHEMBL7722612 0.86 PRMT6 (0.38) PPARDPPARAPPARGSERPINE1PRMT6
SCHEMBL7723050 0.86 KIF11 (0.36) PRMT6FFAR4FFAR1
SCHEMBL7730134 0.86 PRMT6 (0.32) PRMT6FFAR4FFAR1PDE2AALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed