Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722882 | 0.94 | DAO (0.40) | ARTRPV4CYP11B1CYP11B2DAO | |
| SCHEMBL7732790 | 0.93 | NPC1 (0.37) | ARTRPV4CYP11B1CYP11B2DAO | |
| SCHEMBL7731592 | 0.92 | TSHR (0.39) | ARTRPV4CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7735351 | 0.90 | TRPV4 (0.39) | ARTRPV4CYP11B1CYP11B2ACACB | |
| SCHEMBL7732553 | 0.87 | DAO (0.39) | ARTRPV4CYP11B1CYP11B2DAO | |
| SCHEMBL7730247 | 0.87 | DAO (0.40) | ARTRPV4CYP11B1CYP11B2DAO | |
| SCHEMBL7733192 | 0.86 | ALPL (0.34) | ARTRPV4CTSSCTSKKDM4E | |
| SCHEMBL7729846 | 0.86 | DAO (0.38) | ARTRPV4CYP11B1CYP11B2DAO | |
| SCHEMBL7729700 | 0.86 | TRPV4 (0.35) | ARTRPV4CYP11B1CYP11B2 | |
| SCHEMBL7729698 | 0.86 | TRPV4 (0.35) | ARTRPV4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |