Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918889 | 0.98 | MAPT (0.39) | GPR84RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL9868672 | 0.81 | — | — | |
| SCHEMBL7734381 | 0.80 | KCNH2 (0.40) | RAB9AMAPTSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL10602451 | 0.79 | RAB9A (0.50) | GPR84RAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL11751999 | 0.79 | TSHR (0.62) | RAB9ASMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL10601094 | 0.79 | TSHR (0.62) | RAB9ASMN1; SMN2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL8917053 | 0.79 | MAPT (0.65) | RAB9AMAPTSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL7677484 | 0.79 | MAPT (0.65) | RAB9AMAPTSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL10743226 | 0.78 | MAPT (0.57) | RAB9AMAPTSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL8552964 | 0.78 | RAB9A (0.49) | GPR84RAB9AMAPTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929508-B1 | LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2002-03-20 | — | — | EP | disclosed |
| EP-0929508-A1 | LIQUID CRYSTALLINE ($i(E,E))-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013325-A1 | LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1998-04-02 | — | — | WO | disclosed |