Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733676 | 0.98 | GPR84 (0.37) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9868672 | 0.82 | — | — | |
| SCHEMBL7677484 | 0.80 | MAPT (0.65) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL8917053 | 0.80 | MAPT (0.65) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL10743226 | 0.80 | MAPT (0.57) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL8875432 | 0.80 | MAPT (0.57) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL8552964 | 0.80 | RAB9A (0.49) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL17225132 | 0.80 | HSD17B10 (0.65) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL11757976 | 0.80 | HSD17B10 (0.65) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL11749328 | 0.80 | HSD17B10 (0.65) | MAPTRAB9AHSD17B10SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5651918-A | Optically active 1,3-dioxolane derivatives carrying a mesogenic radical in the 4-position, a process for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| US-5384070-A | Use of optically active tetrahydrofuran-2-carboxylic acid esters as dopants in liquid-crystal mixtures, liquid-crystal mixtures containing same and novel optically active tetrahydrofuran-2-carboxylic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-24 | — | — | US | disclosed |
| US-4988459-A | Electrooptic switches or display | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0355008-A2 | Organosilylalkyl or -alkenyl compounds, process for their preparation and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-21 | — | — | EP | disclosed |