SCHEMBL7733741

SCHEMBL7733741

C=C(C)c1ccc(OC#N)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
PDE4A P27815 2/20 0.33
PDE4B Q07343 2/20 0.33
PDE4C Q08493 2/20 0.33
PDE4D Q08499 2/20 0.33
ELANE P08246 1/20 0.33
NQO2 P16083 1/20 0.31
PARP15 Q460N3 1/20 0.31
PARP10 Q53GL7 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KMT2A Q03164 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL29246398 0.96 ELANE (0.38) MAPTALDH1A1HPGDRAB9APDE4A
SCHEMBL29132649 0.83 MAPT (0.38) MAPTALDH1A1HPGDRAB9APDE4A
SCHEMBL11856798 0.79 MAPT (0.59) MAPTALDH1A1HPGDRAB9AL3MBTL1
SCHEMBL15224678 0.79 PSMB1 (0.39) MAPTALDH1A1HPGDRAB9APDE4A
SCHEMBL24787 0.76 CA1 (0.32) MAPTALDH1A1HPGD
SCHEMBL5820050 0.75 HPGD (0.58) MAPTALDH1A1HPGDRAB9APARP15
SCHEMBL764016 0.75 ACHE (0.48) MAPTALDH1A1RAB9AKMT2A
SCHEMBL8397356 0.75 POLB (0.40) MAPTALDH1A1HPGDKMT2A
SCHEMBL10704889 0.75 MAPT (0.44) MAPTALDH1A1HPGDRAB9APARP10
SCHEMBL1742767 0.74 STS (0.45) MAPTALDH1A1HPGDRAB9AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4600760-A Thermosettable resin composition containing alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1986-07-15 US claimed
US-4581425-A WITH AROMATIC POLYCYANATE, POLYMALEIMIDE, AND UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1986-04-08 US claimed
US-4578439-A Styryl pyridine cyanates, styryl pyrazine cyanates and polymers thereof THE DOW CHEMICAL COMPANY (US) 1986-03-25 US claimed
US-4559399-A CURABLE MIXTURE OF ALKENYLPHENYL CYANATE, AROMATIC POLYCYANATE ANDUNSATURATED COMPOUND; HIGH STRENGH POLYTRIAZINES THE DOW CHEMICAL COMPANY (US) 1985-12-17 US claimed
US-4558115-A Thermosettable resin compositions containing a polyepoxide and an alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1985-12-10 US claimed
US-6399666-B1 FOR MICROCIRCUIT; DECOMPOSABLE POLYMER AND DIELECTRIC INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-06-04 US disclosed
US-6093636-A FORMING ON A SUBSTRATE A DIELECTRIC LAYER COMPRISING DECOMPOSABLE POLYMER AND THERMOSETTING RESIN; HEATING TO CURE THE THERMOSETTING RESIN; DECOMPOSING THE DECOMPOSABLE POLYMER; LITOGRAPHIC PATTERNING; DEPOSITING A METALLIC FILM INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2000-07-25 US disclosed
EP-0409069-B1 Mesogenic polycyanates and polycyanamides and thermosets thereof DOW CHEMICAL CO (US) 1999-06-02 EP disclosed
EP-0409070-B1 Mesogenic cyanite functional maleimides and thermosets thereof DOW CHEMICAL CO (US) 1999-03-03 EP disclosed
US-5612479-A Polyphenols containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1997-03-18 US disclosed
US-5470946-A Products resulting from polymerizing or curing polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1995-11-28 US disclosed
US-5442039-A Rod-like mesogenic structures incorporated into polytriazine products; improved tensile strength, flexural strength THE DOW CHEMICAL COMPANY (US) 1995-08-15 US disclosed
US-4629764-A EPOXIDES COMPRISING GLYCIDOL, POLYPHENOL AND COPOLYMERIZED ALKENYL PHENO ADDITION POLYMER; HIGH STRENGTH THE DOW CHEMICAL COMPANY (US) 1986-12-16 US disclosed
US-4611022-A A MIXTURE OF A POLYPHENOL COMPOUND AND A POLYMER OF AN ALKENYL PHENOL AND UNSATURATED MONOMER; POLYEPOXIDES AND-CYANURATES THE DOW CHEMICAL COMPANY (US) 1986-09-09 US disclosed
US-4600760-A Thermosettable resin composition containing alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1986-07-15 US disclosed
US-4581425-A WITH AROMATIC POLYCYANATE, POLYMALEIMIDE, AND UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1986-04-08 US disclosed
US-4578439-A Styryl pyridine cyanates, styryl pyrazine cyanates and polymers thereof THE DOW CHEMICAL COMPANY (US) 1986-03-25 US disclosed
US-4559399-A CURABLE MIXTURE OF ALKENYLPHENYL CYANATE, AROMATIC POLYCYANATE ANDUNSATURATED COMPOUND; HIGH STRENGH POLYTRIAZINES THE DOW CHEMICAL COMPANY (US) 1985-12-17 US disclosed
US-4558115-A Thermosettable resin compositions containing a polyepoxide and an alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1985-12-10 US disclosed
US-4546131-A COPOLYMERS OF ETHYLENICALLY UNSATURATED COMPOUNDS AND ALKENYLPHENYL CYANATE THE DOW CHEMICAL COMPANY (US) 1985-10-08 US disclosed