SCHEMBL8397356

SCHEMBL8397356

C=C(C)Cc1ccc(OC#N)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
MAPT P10636 3/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
GALK1 P51570 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
CALM1 P0DP23 1/20 0.31
ALDH1A1 P00352 2/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21427450 0.82 F2RL1 (0.38) POLBSMN1; SMN2MAPTMEN1LMNA
SCHEMBL28538303 0.81 POLB (0.61) POLBHTTSMN1; SMN2MAPTLMNA
SCHEMBL6015468 0.77 ALDH1A1 (0.38) POLBHTTSMN1; SMN2MAPTMEN1
SCHEMBL22478850 0.75
SCHEMBL23230152 0.75 SMN1; SMN2 (0.46) SMN1; SMN2MAPTMEN1LMNAKMT2A
SCHEMBL7733741 0.75 MAPT (0.37) MAPTKMT2AALDH1A1HPGD
SCHEMBL13756085 0.75 KMT2A (0.39) POLBHTTSMN1; SMN2MAPTMEN1
SCHEMBL23841233 0.74 LTA4H (0.48) MEN1TSHRKMT2A
SCHEMBL3810021 0.74 CYP2A6 (0.52) SMN1; SMN2MAPTMEN1LMNATP53
SCHEMBL10401975 0.74 CALM1 (0.44) POLBTSHRCALM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4600760-A Thermosettable resin composition containing alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1986-07-15 US claimed
US-4581425-A WITH AROMATIC POLYCYANATE, POLYMALEIMIDE, AND UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1986-04-08 US claimed
US-4558115-A Thermosettable resin compositions containing a polyepoxide and an alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1985-12-10 US claimed
EP-0409069-B1 Mesogenic polycyanates and polycyanamides and thermosets thereof DOW CHEMICAL CO (US) 1999-06-02 EP disclosed
EP-0409070-B1 Mesogenic cyanite functional maleimides and thermosets thereof DOW CHEMICAL CO (US) 1999-03-03 EP disclosed
US-5612479-A Polyphenols containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1997-03-18 US disclosed
US-5470946-A Products resulting from polymerizing or curing polycyanates containing mesogenic moieties as lateral substituents THE DOW CHEMICAL COMPANY (US) 1995-11-28 US disclosed
US-5442039-A Rod-like mesogenic structures incorporated into polytriazine products; improved tensile strength, flexural strength THE DOW CHEMICAL COMPANY (US) 1995-08-15 US disclosed
US-5428125-A Liquid crystalline THE DOW CHEMICAL COMPANY (US) 1995-06-27 US disclosed
US-5399673-A Polymerizable monomers THE DOW CHEMICAL COMPANY (US) 1995-03-21 US disclosed
US-5248757-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5159030-A Molecular orientated, curable liquid crystal THE DOW CHEMICAL COMPANY (US) 1992-10-27 US disclosed
US-5077380-A Mesogenic cyanate functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-12-31 US disclosed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
EP-0409070-A2 Mesogenic cyanite functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
US-4600760-A Thermosettable resin composition containing alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1986-07-15 US disclosed
US-4581425-A WITH AROMATIC POLYCYANATE, POLYMALEIMIDE, AND UNSATURATED AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1986-04-08 US disclosed
US-4559399-A CURABLE MIXTURE OF ALKENYLPHENYL CYANATE, AROMATIC POLYCYANATE ANDUNSATURATED COMPOUND; HIGH STRENGH POLYTRIAZINES THE DOW CHEMICAL COMPANY (US) 1985-12-17 US disclosed
US-4558115-A Thermosettable resin compositions containing a polyepoxide and an alkenyl phenyl cyanate THE DOW CHEMICAL COMPANY (US) 1985-12-10 US disclosed
US-4546131-A COPOLYMERS OF ETHYLENICALLY UNSATURATED COMPOUNDS AND ALKENYLPHENYL CYANATE THE DOW CHEMICAL COMPANY (US) 1985-10-08 US disclosed