Thiabendazole

Thiabendazole

SCHEMBL7733801

[Ag].c1ccc2[nH]c(-c3cscn3)nc2c1

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 9/20 0.97
METAP2 P50579 7/20 0.97
NPC1 O15118 5/20 0.97
RAB9A P51151 5/20 0.97
SMN1; SMN2 Q16637 5/20 0.97
TP53 P04637 4/20 0.97
KDM4E B2RXH2 4/20 0.97
FKBP1A P62942 2/20 0.97
ADORA3 P0DMS8 2/20 0.97
TSHR P16473 2/20 0.97
CYP1A2 P05177 1/20 0.97
CYP3A4 P08684 1/20 0.97
CYP2D6 P10635 1/20 0.97
CYP2C19 P33261 1/20 0.97
HIF1A Q16665 1/20 0.97
TDP1 Q9NUW8 1/20 0.97
HDAC6 Q9UBN7 1/20 0.97
PKM P14618 3/20 0.57
HPGD P15428 2/20 0.57
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiabendazole SCHEMBL625588 0.98 METAP1 (1.00) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL19842 0.98 METAP1 (1.00) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL29370729 0.98 METAP1 (1.00) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL28861440 0.97 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL2314460 0.97 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL11218788 0.97 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL5184037 0.97 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL9856779 0.97 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL27856286 0.97 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL28110806 0.91 METAP1 (0.86) METAP1METAP2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104211721-A Keggin type crystalline material based on modification of thiabendazole silver complex, as well as synthesis method and application of Keggin type crystalline material in aspect of Hg<2+> ion sensing UNIV BOHAI 2014-12-17 CN claimed
CN-109097991-A A kind of mite-proofing and antimicrobial method for sorting of fleece fabrics 江苏阳光毛纺服装技术开发有限公司 2018-12-28 CN disclosed
CN-104211721-B Keggin type crystalline material based on modification of thiabendazole silver complex, as well as synthesis method and application of Keggin type crystalline material in aspect of Hg2+ ion sensing 渤海大学 2017-02-08 CN disclosed
CN-104211721-B Keggin type crystalline material based on modification of thiabendazole silver complex, as well as synthesis method and application of Keggin type crystalline material in aspect of Hg2+ ion sensing 渤海大学 2017-02-08 CN disclosed
CN-104211721-A Keggin type crystalline material based on modification of thiabendazole silver complex, as well as synthesis method and application of Keggin type crystalline material in aspect of Hg<2+> ion sensing UNIV BOHAI 2014-12-17 CN disclosed
CN-104211721-A Keggin type crystalline material based on modification of thiabendazole silver complex, as well as synthesis method and application of Keggin type crystalline material in aspect of Hg<2+> ion sensing UNIV BOHAI 2014-12-17 CN disclosed
CN-104211721-A Keggin type crystalline material based on modification of thiabendazole silver complex, as well as synthesis method and application of Keggin type crystalline material in aspect of Hg<2+> ion sensing UNIV BOHAI 2014-12-17 CN disclosed
US-6403050-B1 ION EXCHANGING WITH SILVER KUNIMINE INDUSTRIES CO., LTD. (JP) 2002-06-11 US disclosed
EP-1048616-A2 Calcium silicates, a production process thereof, and an inorganic antibacterial material using the same KUNIMINE INDUSTRIES CO. LTD. (JP) 2000-11-02 EP disclosed