Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 9/20 | 0.97 |
| ▸ | METAP2 | P50579 | 7/20 | 0.97 |
| ▸ | NPC1 | O15118 | 5/20 | 0.97 |
| ▸ | RAB9A | P51151 | 5/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.97 |
| ▸ | TP53 | P04637 | 4/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.97 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.97 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.97 |
| ▸ | TSHR | P16473 | 2/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.97 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.97 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiabendazole SCHEMBL19842 | 0.98 | METAP1 (1.00) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL29370729 | 0.98 | METAP1 (1.00) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL625588 | 0.98 | METAP1 (1.00) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL28861440 | 0.97 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL2314460 | 0.97 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL11218788 | 0.97 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL5184037 | 0.97 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL7733801 | 0.97 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL27856286 | 0.97 | METAP1 (0.97) | METAP1METAP2NPC1RAB9ASMN1; SMN2 | |
| Thiabendazole SCHEMBL27509072 | 0.91 | METAP1 (0.86) | METAP1METAP2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070938-A | Having two layer protective coating; conversion film with a metal and antimicrobial film which bonds with it | NIPPONDENSO CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |