Thiabendazole

Thiabendazole

SCHEMBL19842

c1ccc2[nH]c(-c3cscn3)nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 9/20 1.00
METAP2 P50579 7/20 1.00
NPC1 O15118 6/20 1.00
RAB9A P51151 6/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
TP53 P04637 4/20 1.00
KDM4E B2RXH2 3/20 1.00
FKBP1A P62942 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
TSHR P16473 2/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C19 P33261 1/20 1.00
HIF1A Q16665 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
HDAC6 Q9UBN7 1/20 1.00
PKM P14618 3/20 0.58
HPGD P15428 2/20 0.58
LMNA P02545 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiabendazole SCHEMBL625588 1.00 METAP1 (1.00) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL29370729 1.00 METAP1 (1.00) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL5184037 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL2314460 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL11218788 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL7733801 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL28861440 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL9856779 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL675655 0.91 METAP1 (0.83) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL675656 0.91 METAP1 (0.83) METAP1METAP2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 63992 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104643-A1 MIXTURES FOR CONTROLLING INFESTATION OF PLANTS SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 WO claimed
WO-2026105160-A1 NOVEL AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2026-05-21 WO claimed
US-12630744-B2 Polishing compositions and methods of use thereof FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2026-05-19 US claimed
CN-122056270-A Pesticide suspension concentrate and fertilizer composition thereof 诺力昂化学品国际有限公司 2026-05-19 CN claimed
CN-122037502-A Antibacterial low-temperature polycaprolactone composition suitable for microwave heating and preparation method and application thereof 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-121574628-B Aluminum profile spraying powder coating and preparation method thereof 佛山职业技术学院 2026-05-12 CN claimed
EP-4736642-A2 WOOD TREATMENT SOLUTIONS CONTAINING FUNGICIDES AND TERTIARY ALKANOLAMINES AND RELATED METHODS, WOOD PRODUCTS AND COMPOSITION FOR PROTECTION AGAINST FUNGAL ORGANISMS KOP-COAT, INC. (US) 2026-05-06 EP claimed
EP-4447665-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-04-22 EP claimed
EP-4727359-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-04-22 EP claimed
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
EP-0041114-A2 Process for the preparation of medicated animal feed supplement AMERICAN CYANAMID COMPANY (US) 1981-12-09 EP claimed
US-4302467-A SORBIC ACID OR SALTS THEREOF AND 2-(4-THIAZOLYL)-1H-BENZIMIDAZOLE NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-11-24 US claimed
EP-0006212-B1 SYSTEM OF PULVERISATION IN THE FORM OF AN AEROSOL Airwick AG (CH) 1981-08-05 EP claimed
US-4247442-A Mold and mildew resistant organopolysiloxane compositions TORAY SILICONE COMPANY, LTD. (JP) 1981-01-27 US claimed
EP-0006212-A1 System of pulverisation in the form of an aerosol Airwick AG (CH) 1980-01-09 EP claimed
US-4120970-A 2-(4-THIAZOLYL) BENZIMIDAZOLE AND AN ALKALI METAL SALT OF ORTHO-PHENYL PHENOL TETRAHYDRATE BROGDEX COMPANY (US) 1978-10-17 US claimed
US-4020016-A NITRILOTRIACETIC ACID SALT, AND AN ALKYLENE POLYAMINE POLYCARBOXYLIC ACID THE DRACKETT COMPANY (US) 1977-04-26 US claimed
US-4009266-A METHOD OF TREATMENT OF NEMATODE PARASITE INFECTIONS IN DOMESTIC ANIMALS AYALEW LIYEW 1977-02-22 US claimed
US-3998785-A OR ANTI-BACTERIAL HARDWARE FOR INK PRINTING APPARATUS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1976-12-21 US claimed
US-3962430-A Sterilization of solid non-electrolyte medicinal agents employing sodium chloride MERCK & CO., INC. (US) 1976-06-08 US claimed