Thiabendazole

Thiabendazole

SCHEMBL29370729

c1ccc2[nH]c(-c3cscn3)nc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 9/20 1.00
METAP2 P50579 7/20 1.00
NPC1 O15118 6/20 1.00
RAB9A P51151 6/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
TP53 P04637 4/20 1.00
KDM4E B2RXH2 3/20 1.00
FKBP1A P62942 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
TSHR P16473 2/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C19 P33261 1/20 1.00
HIF1A Q16665 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
HDAC6 Q9UBN7 1/20 1.00
PKM P14618 3/20 0.58
HPGD P15428 2/20 0.58
LMNA P02545 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiabendazole SCHEMBL625588 1.00 METAP1 (1.00) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL19842 1.00 METAP1 (1.00) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL5184037 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL2314460 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL11218788 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL7733801 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL28861440 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL9856779 0.98 METAP1 (0.97) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL675655 0.91 METAP1 (0.83) METAP1METAP2NPC1RAB9ASMN1; SMN2
Thiabendazole SCHEMBL675656 0.91 METAP1 (0.83) METAP1METAP2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-20260041088-A1 WOOD TREATMENT SOLUTIONS CONTAINING FUNGICIDES AND TERTIARY ALKANOLAMINES AND RELATED METHODS, WOOD PRODUCTS AND COMPOSITION FOR PROTECTION AGAINST FUNGAL ORGANISMS KOP COAT INC (US) 2026-02-12 US claimed
EP-4543441-A2 TOPICAL BENZIMIDAZOLE FORMULATIONS AND METHODS FOR USE IN TREATING INFLAMMATORY DERMATOSES JJR&D, LLC (US) 2025-04-30 EP claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 US claimed
CN-116285407-B High-fluidity tea residue/polypropylene composite material and preparation method thereof 韩山师范学院 2024-10-15 CN claimed
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
EP-4422402-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
CN-118373837-A 2- (4' -Thiazolyl) benzimidazole copper complex and preparation method and application thereof 邵阳学院 2024-07-23 CN claimed
EP-3890958-B1 DECORATIVE PANEL, AND DECORATIVE FLOOR COVERING CONSISTING OF SAID PANELS I4F LICENSING NV (BE) 2024-05-01 EP claimed
CN-117917401-A Triphenylamine derivative photosensitizer for inducing tumor macrophage polarization to M1 phenotype and preparation method and application thereof 天津工业大学 2024-04-23 CN claimed
WO-2023249992-A2 TOPICAL BENZIMIDAZOLE FORMULATIONS AND METHODS FOR USE IN TREATING INFLAMMATORY DERMATOSES JJR&D, LLC (US) 2023-12-28 WO claimed
EP-4247321-A1 PERSONAL CARE COMPOSITIONS FREE OF SULFATED SURFACTANTS The Procter & Gamble Company (US) 2023-09-27 EP claimed
CN-116801720-A Novel agrochemical compositions comprising 3-substituted benzamidine compounds and uses thereof 皮埃企业有限公司 2023-09-22 CN claimed
CN-116285407-A High-fluidity tea residue/polypropylene composite material and preparation method thereof 韩山师范学院 2023-06-23 CN claimed
WO-2023072784-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
WO-2023072785-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
EP-4059348-A1 MIXTURE OF A FOLCYSTEINE-BASED BIOSTIMULANT AND AN AGROTOXIC SUBSTANCE OF INTEREST RESULTING IN A QUANTITATIVELY, QUALITATIVELY AND TIME-RELATED RESULT-POTENTIATING ACTION AS OBSERVED IN AN AGRICULTURAL CROP OF A PLANT OF INTEREST UPL Corporation Limited (MU) 2022-09-21 EP claimed
US-20220279784-A1 Mixture of a Folcysteine-Based Biostimulant and an Agrotoxic Substance of Interest Resulting in a Quantitatively, Qualitatively and Time-Related Result-potentiating Action as Observed in an Agricultural Crop of a Plant of Interest UPL Corporation Limited (MU) 2022-09-08 US claimed
WO-2022109094-A1 PERSONAL CARE COMPOSITIONS FREE OF SULFATED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 2022-05-27 WO claimed
CN-114044784-A Sulfur-coordinated mononuclear cobalt monomolecular magnet and preparation method and application thereof 江苏科技大学 2022-02-15 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017207-A1 FUNGICIDAL COMPOSITIONS CYP51A1, BROX, DPM1 METAP1 681/4885METAP2 713/4885NPC1 2315/4885
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL NOTUM, CTRL, BROX METAP1 718/4885METAP2 796/4885NPC1 2915/4885
US-20260041088-A1 WOOD TREATMENT SOLUTIONS CONTAINING FUNGICIDES AND TERTIARY ALKANOLAMINES AND RELATED METHODS, WOOD PRODUCTS AND COMPOSITION FOR PROTECTION AGAINST FUNGAL ORGANISMS ERG28, TET1, SETD2 METAP1 434/4885METAP2 593/4885NPC1 1439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.