Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230288 | 0.83 | GAA (0.43) | GBA1GAAEPHX2DDB1CRBN | |
| SCHEMBL7736582 | 0.83 | GAA (0.43) | GBA1GAAEPHX2DDB1CRBN | |
| SCHEMBL18622663 | 0.83 | CA12 (0.46) | GBA1GAAEPHX2DDB1CRBN | |
| SCHEMBL7733793 | 0.80 | KDM4E (0.43) | GBA1GAAKDM4EGLATSHR | |
| SCHEMBL2093975 | 0.79 | CHRM2 (0.49) | GBA1GAAEPHX2DDB1CRBN | |
| SCHEMBL18646045 | 0.79 | GAA (0.40) | GBA1GAAEPHX2DDB1CRBN | |
| SCHEMBL6235230 | 0.79 | GAA (0.45) | GBA1GAAEPHX2DDB1CRBN | |
| SCHEMBL14122137 | 0.78 | CHRM2 (0.48) | GBA1GAAEPHX2DDB1CRBN | |
| SCHEMBL27764586 | 0.77 | KDM4E (0.46) | GBA1GAAKDM4EGLAUSP2 | |
| SCHEMBL3073595 | 0.77 | CHRM2 (0.62) | GBA1GAAKDM4EGLAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466920-A1 | METHOD FOR OBTAINING -AMINO ALCOHOLS | Universitat de València (ES) | 2019-04-10 | — | — | EP | disclosed |
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |