Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.43 |
| ▸ | GBA1 | P04062 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723877 | 0.84 | MRGPRX1 (0.40) | KDM4EMRGPRX1MEN1S1PR2S1PR4 | |
| SCHEMBL7733811 | 0.80 | GBA1 (0.54) | KDM4EGLAGBA1GAAHTT | |
| SCHEMBL11142854 | 0.80 | TDP1 (0.54) | KDM4EGLAGBA1LMNAHTT | |
| SCHEMBL8470228 | 0.78 | ALDH1A1 (0.55) | KDM4EGLAGBA1LMNAGAA | |
| SCHEMBL22729471 | 0.76 | MRGPRX1 (0.40) | KDM4EMRGPRX1MEN1S1PR2S1PR4 | |
| SCHEMBL18884397 | 0.76 | L3MBTL1 (0.48) | KDM4EMRGPRX1MEN1S1PR2S1PR4 | |
| SCHEMBL22593391 | 0.76 | MRGPRX1 (0.43) | KDM4EMRGPRX1MEN1S1PR2S1PR4 | |
| SCHEMBL12017388 | 0.76 | APP (0.50) | KDM4EMRGPRX1MEN1S1PR2S1PR4 | |
| Hydrochloric Acid SCHEMBL10533927 | 0.75 | L3MBTL1 (0.52) | KDM4EMRGPRX1MEN1S1PR2S1PR4 | |
| Hydrochloric Acid SCHEMBL28062296 | 0.75 | APP (0.49) | KDM4EMRGPRX1MEN1S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |